南華大學公共衛生學院導師：周平坤 正文

[導師姓名]
周平坤

[所屬院校]
南華大學

[基本信息]
導師姓名：周平坤
性別：男
人氣指數：3000
所屬院校：南華大學
所屬院系：公共衛生學院
職稱：研究員
導師類型：
招生專業：衛生毒理學

[通訊方式]
辦公電話：010-68183899
電子郵件：zhoupkek@aliyun.com
通訊地址：北京市海淀區太平路27號院

[個人簡述]
1.放射致基因組損傷效應基礎危害評價和防護研究，獲中國人民解放軍科學技術進步獎一等獎，周平坤為第一完成人，2015年10月。
2.2015年獲總后二等功，
3.亞洲輻射研究協會（AARR）授予“輻射研究杰出貢獻獎”2013年5月。

[科研工作]
1985/07-至今軍事醫學科學院，放射與輻射醫學研究所，研究員1998/03-2000/03 法國居里研究所（訪問）研究員2013-至今蘇州大學，客座教授1. Shi HM, Ding KK, Zhou PK, Guo DM, Chen D, Li YS, Zhao CL, Zhao CC, Zhang X. Radiation-induced expression of IER5 is dose-dependent and not associated with the clinical outcomes of radiotherapy in cervical cancer. Oncol Lett. 2016 Feb11(2):1309-1314. Epub 2016 Jan 82. Liu F, Ren C, Li H, Zhou P, Bo X, Shu W. De novo Identification of replication-timing domains in the human genome by deep learning. Bioinformatics, 2015 Nov 5. pii: btv643.3. Xiong S, Pan X, Xu L, Yang Z, Guo R, Gu Y, Li R, Wang Q, Xiao F, Du L, Zhou P, Zhu M. Regulatory T Cells Promote β-Catenin-Mediated Epithelium-to-Mesenchyme Transition During Radiation-Induced Pulmonary Fibrosis. Int J Radiat Oncol Biol Phys, 2015 Oct 1 93(2):425-35. 4. Song N, Ma X, Li H, Zhang Y, Wang X, Zhou P, Zhang X. microRNA-107 functions as a candidate tumor suppressor gene in renal clear cell carcinoma involving multiple genes. Urol Oncol. 2015 May33(5):205.e1-11.5. Shang ZF, Tan W, Liu XD, Yu L, Li B, Li M, Song M, Wang Y, Xiao BB, Zhong CG, Guan H*, Zhou PK*. DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway. Int J Biol Sci. 2015 Jul 1411(9):1026-35. 6. Cui F, Fan R, Chen Q, He Y, Song M, Shang Z, Zhang S, Zhu W, Cao J, Guan H, Zhou PK*. The involvement of c-Myc in the DNA double-strand break repair via regulating radiation-induced phosphorylation of ATM and DNA-PKcs activity. Mol Cell Biochem. 2015 Aug406(1-2):43-51. 7. Zou LH, Shang ZF*, Tan W, Liu XD, Xu QZ, Song M, Wang Y, Guan H, Zhang SM, Yu L, Zhong CG, Zhou PK*. TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1. Oncotarget. 2015, 6(9): 7011-7022.8. Zhang SM, Shang F, Zhou PK*. Autophagy as the effector and player in DNA damage response of cells to genotoxicants. Toxicology Research, 2015, 4: 613-622 3.2739. Li MJ, Cui F, Cheng Y, Han L, Wang J, Sun D, Liu YL, Zhou PK*, Min R*. Gelsolin: Role of a Functional Protein in Mitigating Radiation Injury. Cell Biochem Biophys, 2015, 71(1): 389-396 2.3810. Zhang SM*, Zhang H, Yang TY, Ying TY, Yang PX, Liu XD, Tang SJ, Zhou PK*. Interaction between HIV-1 Tat and DNA-PKcs modulates HIV transcription and class switch recombination. Int J Biol Sci. 2014 10(10):1138-49. 11. Huang B, Shang ZF, Li B, Wang Y, Liu XD, Zhang SM, Guan H, Rang WQ, Hu JA, Zhou PK*. DNA-PKcs associates with PLK1 and is involved in proper chromosome segregation and cytokinesis. J Cell Biochem. 2014 115(6):1077-88.12. Tu WZ, Li B, Huang B, Wang Y, Liu XD, Guan H, Zhang SM, Tang Y, Rang WQ*, Zhou PK*. γH2AX foci formation in the absence of DNA damage: mitotic H2AX phosphorylation is mediated by the DNA-PKcs/CHK2 pathway. FEBS Lett. 2013 587(21):3437-43. 13. Li B, Shang ZF, Yin JJ, Xu QZ, Liu XD, Wang Y, Zhang SM, Guan H, Zhou PK*. PIG3 functions in DNA damage response through regulating DNA-PKcs homeostasis. Int J Biol Sci. 2013 9(4):425-34. 14. Shang ZF, Yu L, Li B, Tu WZ, Wang Y, Liu XD, Guan H, Huang B, Rang WQ, Zhou PK*.4E-BP1 participates in maintaining spindle integrity and genomic stability via interacting with PLK1. Cell Cycle. 2012 11(18):3463-71.15. Zhang SM, Song M, Yang TY, Fan R, Liu XD, Zhou PK*. HIV-1 Tat impairs cell cycle control by targeting the Tip60, Plk1 and cyclin B1 ternary complex. Cell Cycle. 201211(6):1217-34.16. Zhang B, Huang B, Guan H, Zhang SM, Xu QZ, He XP, Liu XD, Wang Y, Shang ZF, Zhou PK*. Proteomic profiling revealed the functional networks associated with mitotic catastrophe of HepG2 hepatoma cells induced by 6-bromine-5-hydroxy-4-methoxybenzaldehyde. Toxicol Appl Pharmacol. 2011 252(3):307-17.17. Shang ZF, Huang B, Xu QZ, Zhang SM, Fan R, Liu XD, Wang Y, Zhou PK*. Inactivation of DNA-dependent protein kinase leads to spindle disruption and mitotic catastrophe with attenuated checkpoint protein 2 Phosphorylation in response to DNA damage. Cancer Res. 2010 70(9):3657-66.18. An J, Yang TY, Huang YC, Liu F, Sun JF, Wang Y, Xu QZ, Wu DC, Zhou PK. Strand-specific PCR of UV radiation-damaged genomic DNA revealed an essential role of DNA-PKcs in the transcription-coupled repair. BMC Biochemistry, 2011, 12:2. doi:10.1186/1471-2091-12-2. 1.766湖南省芙蓉學者特聘教授南華大學公共衛生學院教授、環境醫學與放射衛生研究所所長中國毒理學會理事長國際放射防護委員會（ICRP）委員中國輻射防護學會常委中華醫學會放射醫學與防護分會常委Toxicology Research副主編Food and Chemical Toxicology副主編International Journal of Radiation Biology編輯顧問委員會委員中國科學院重離子束輻射生物醫學重點實驗室學術委員會主任中國航天醫學基礎與應用國家重點實驗室學術委員會委員國家自然科學基金委生命科學部和醫學科學部評審專家

[教育背景]
1980/09-1985/07 中南大學，湘雅醫學院，學士
1987/09-1990/07軍事醫學科學院，放射與輻射醫學研究所，碩士，導師：魏康
2001/09-2004/06軍事醫學科學院，放射與輻射醫學研究所，博士，導師：吳德昌 以上老師的信息來源于學校網站，如有更新或錯誤，請聯系我們進行更新或刪除，聯系方式

南華大學

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